Survival of patients treated with radiation therapy for anaplastic astrocytoma.

ABSTRACT:

Background

Anaplastic astrocytoma (AA) represents 7% of primary brain tumors in adults. Patient-, tumor-, and treatment-related factors are thought to be predictive of survival. We retrospectively assessed the association of patient-, tumor-, and treatment-related factors with survival in AA treated with radiotherapy (RT) at our institution.

Patients and methods

Medical records of patients with AA treated with RT between 1987 and 2007 were reviewed. Patient-, tumor-, and treatment-related variables were recorded and used to assign patients to a Radiation Therapy Oncology Group recursive partitioning analysis (RTOG RPA) classification. First use of chemotherapy was recorded. Log-rank tests and Cox regression models were used to assess for an association of patient-, tumor- an

SUBMITTER: Barker CA 

PROVIDER: S-EPMC4230558 | biostudies-literature | 2014 Dec

REPOSITORIES: biostudies-literature