Highly variable recombinational landscape modulates efficacy of natural selection in birds.

ABSTRACT: Determining the rate of protein evolution and identifying the causes of its variation across the genome are powerful ways to understand forces that are important for genome evolution. By using a multitissue transcriptome data set from great tit (Parus major), we analyzed patterns of molecular evolution between two passerine birds, great tit and zebra finch (Taeniopygia guttata), using the chicken genome (Gallus gallus) as an outgroup. We investigated whether a special feature of avian genomes, the highly variable recombinational landscape, modulates the efficacy of natural selection through the effects of Hill-Robertson interference, which predicts that selection should be more effective in removing deleterious mutations and incorporating beneficial mutations in high-recombination regions

SUBMITTER: Gossmann TI 

PROVIDER: S-EPMC4231635 | biostudies-literature | 2014 Aug

REPOSITORIES: biostudies-literature