Interval lung cancers not detected on screening chest X-rays: How are they different?

ABSTRACT:

Background

The Prostate, Lung, Colorectal and Ovarian Cancer Screening Trial provides us an opportunity to describe interval lung cancers not detected by screening chest X-ray (CXR) compared to screen-detected cancers.

Methods

Participants were screened for lung cancer with CXR at baseline and annually for two (never smokers) or three (ever smokers) more years. Screen-detected cancers were those with a positive CXR and diagnosed within 12 months. Putative interval cancers were those with a negative CXR screen but with a diagnosis of lung cancer within 12 months. Potential interval cancers were re-reviewed to determine whether lung cancer was missed and probably present during the initial interpretation or whether the lesion was a "true interval" cancer.

Results

77,445

SUBMITTER: Kvale PA 

PROVIDER: S-EPMC4232302 | biostudies-literature | 2014 Oct

REPOSITORIES: biostudies-literature