Ordered, adherent layers of nanofibers enabled by supramolecular interactions.

ABSTRACT: Aligned nanofibrous substrates can be created by electrospinning, but methods for creating multilamellar structures of aligned fibers are limited. Here, apposed nanofibrous scaffolds with pendant β-cyclodextrin (CD) were adhered together by adamantane (Ad) modified hyaluronic acid, exploiting the guest-host interactions of CD and Ad for macroscopic assembly. Stable user-defined multi-layered scaffolds were formed for cell culture or tissue engineering.

SUBMITTER: Highley CB 

PROVIDER: S-EPMC4232958 | biostudies-literature | 2014

REPOSITORIES: biostudies-literature