Modeling and analysis of personal exposures to VOC mixtures using copulas.

ABSTRACT: Environmental exposures typically involve mixtures of pollutants, which must be understood to evaluate cumulative risks, that is, the likelihood of adverse health effects arising from two or more chemicals. This study uses several powerful techniques to characterize dependency structures of mixture components in personal exposure measurements of volatile organic compounds (VOCs) with aims of advancing the understanding of environmental mixtures, improving the ability to model mixture components in a statistically valid manner, and demonstrating broadly applicable techniques. We first describe characteristics of mixtures and introduce several terms, including the mixture fraction which represents a mixture component's share of the total concentration of the mixture. Next, using VOC exposure

SUBMITTER: Su FC 

PROVIDER: S-EPMC4233140 | biostudies-literature | 2014 Feb

REPOSITORIES: biostudies-literature