Onset of virus systemic infection in plants is determined by speed of cell-to-cell movement and number of primary infection foci.

ABSTRACT: The cornerstone of today's plant virology consists of deciphering the molecular and mechanistic basis of host-pathogen interactions. Among these interactions, the onset of systemic infection is a fundamental variable in studying both within- and between-host infection dynamics, with implications in epidemiology. Here, we developed a mechanistic model using probabilistic and spatio-temporal concepts to explain dynamic signatures of virus systemic infection. The model dealt with the inherent characteristic of plant viruses to use two different and sequential stages for their within-host propagation: cell-to-cell movement from the initial infected cell and systemic spread by reaching the vascular system. We identified the speed of cell-to-cell movement and the number of primary infection foci

SUBMITTER: Rodrigo G 

PROVIDER: S-EPMC4233706 | biostudies-literature | 2014 Sep

REPOSITORIES: biostudies-literature