Progressive promoter element combinations classify conserved orthogonal plant circadian gene expression modules.

ABSTRACT: We aimed to test the proposal that progressive combinations of multiple promoter elements acting in concert may be responsible for the full range of phases observed in plant circadian output genes. In order to allow reliable selection of informative phase groupings of genes for our purpose, intrinsic cyclic patterns of expression were identified using a novel, non-biased method for the identification of circadian genes. Our non-biased approach identified two dominant, inherent orthogonal circadian trends underlying publicly available microarray data from plants maintained under constant conditions. Furthermore, these trends were highly conserved across several plant species. Four phase-specific modules of circadian genes were generated by projection onto these trends and, in order to ident

SUBMITTER: Smieszek SP 

PROVIDER: S-EPMC4233729 | biostudies-literature | 2014 Oct

REPOSITORIES: biostudies-literature