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Anti-fibrinolytic use for minimising perioperative allogeneic blood transfusion.


ABSTRACT:

SUBMITTER: Henry DA 

PROVIDER: S-EPMC4234031 | biostudies-literature | 2011 Mar

REPOSITORIES: biostudies-literature

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Anti-fibrinolytic use for minimising perioperative allogeneic blood transfusion.

Henry David A DA   Carless Paul A PA   Moxey Annette J AJ   O'Connell Dianne D   Stokes Barrie J BJ   Fergusson Dean A DA   Ker Katharine K  

The Cochrane database of systematic reviews 20110316 3


<h4>Background</h4>Concerns regarding the safety of transfused blood have led to the development of a range of interventions to minimise blood loss during major surgery. Anti-fibrinolytic drugs are widely used, particularly in cardiac surgery, and previous reviews have found them to be effective in reducing blood loss, the need for transfusion, and the need for re-operation due to continued or recurrent bleeding. In the last few years questions have been raised regarding the comparative performa  ...[more]

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