Safety and efficacy of Nasya/Prevalin in reducing symptoms of allergic rhinitis.

ABSTRACT:

Background

Nasya/Prevalin is a natural, drug-free nasal spray for treatment and prevention of allergic rhinitis. Because of its thixotropic property, it forms a barrier on the nasal mucosa, preventing allergen contact. This study assesses the clinical efficacy and safety of Nasya/Prevalin in a nasal provocation test with house dust mite allergens.

Methodology/principal

In this randomised, double-blind, placebo-controlled trial, 20 subjects suffering from allergic rhinitis because of house dust mite allergens received a single dose of Nasya/Prevalin or saline spray before allergen challenge. Total nasal symptom score and total ocular symptom score were assessed 15, 30, 60, 75, 90, 120 and 240 min after challenge. Further, the appearance of the mucosa was examined by rhinoscop

SUBMITTER: Stoelzel K 

PROVIDER: S-EPMC4235399 | biostudies-literature | 2014 Oct

REPOSITORIES: biostudies-literature