A system based network approach to ethanol tolerance in Saccharomyces cerevisiae.

ABSTRACT:

Background

Saccharomyces cerevisiae has been widely used for bio-ethanol production and development of rational genetic engineering strategies leading both to the improvement of productivity and ethanol tolerance is very important for cost-effective bio-ethanol production. Studies on the identification of the genes that are up- or down-regulated in the presence of ethanol indicated that the genes may be involved to protect the cells against ethanol stress, but not necessarily required for ethanol tolerance.

Results

In the present study, a novel network based approach was developed to identify candidate genes involved in ethanol tolerance. Protein-protein interaction (PPI) network associated with ethanol tolerance (tETN) was reconstructed by integrating PPI data with Gene Ont

SUBMITTER: Kasavi C 

PROVIDER: S-EPMC4236716 | biostudies-literature | 2014 Aug

REPOSITORIES: biostudies-literature