Lateralized resting-state functional connectivity in the task-positive and task-negative networks.

ABSTRACT: Studies on functional brain lateralization using functional magnetic resonance imaging (fMRI) have generally focused on lateralization of local brain regions. To explore the lateralization on the whole-brain level, lateralization of functional connectivity using resting-state fMRI (N=87, right handed) was analyzed and left- and right-lateralized networks were mapped. Four hundred two equally spaced regions of interest (ROI) covering the entire gray matter were divided into 358 task-positive and 44 task-negative ROIs. Lateralization of functional connectivity was analyzed separately for the task-positive and task-negative regions to prevent spuriously high lateralization indices caused by negative correlations between task-positive and task-negative regions. Lateralized functional connectio

SUBMITTER: Di X 

PROVIDER: S-EPMC4238260 | biostudies-literature | 2014 Nov

REPOSITORIES: biostudies-literature