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Predicting recurrence patterns after resection of hepatocellular cancer.


ABSTRACT:

Background

The reliable prediction of hepatocellular carcinoma (HCC) recurrence patterns potentially allows for the prioritization of patients for liver resection (LR) or transplantation.

Objectives

The aim of this study was to analyse clinicopathological factors and preoperative Milan criteria (MC) status in predicting patterns of HCC recurrence.

Methods

During 1992-2012, 320 patients undergoing LR for HCC were categorized preoperatively as being within or beyond the MC, as were recurrences.

Results

After a median follow-up of 47 months, 183 patients developed recurrence, giving a 5-year cumulative incidence of recurrence of 62.5%. Patients with preoperative disease within the MC had better survival outcomes than those with preoperative disease beyond the MC (

SUBMITTER: Lee SY 

PROVIDER: S-EPMC4238862 | biostudies-literature | 2014 Oct

REPOSITORIES: biostudies-literature