Household Transmission of Vibrio cholerae in Bangladesh.

ABSTRACT:

Background

Vibrio cholerae infections cluster in households. This study's objective was to quantify the relative contribution of direct, within-household exposure (for example, via contamination of household food, water, or surfaces) to endemic cholera transmission. Quantifying the relative contribution of direct exposure is important for planning effective prevention and control measures.

Methodology/principal findings

Symptom histories and multiple blood and fecal specimens were prospectively collected from household members of hospital-ascertained cholera cases in Bangladesh from 2001-2006. We estimated the probabilities of cholera transmission through 1) direct exposure within the household and 2) contact with community-based sources of infection. The natural history of

SUBMITTER: Sugimoto JD 

PROVIDER: S-EPMC4238997 | biostudies-literature | 2014 Nov

REPOSITORIES: biostudies-literature