Incident user cohorts for assessing medication cost-offsets.

ABSTRACT:

Objective

To develop and test incident drug user designs for assessing cost savings from statin use in diabetics.

Data source

Random 5 percent sample of Medicare beneficiaries, 2006-2008.

Study design

Seven-step incident user design to assess impact of statin initiation on subsequent Medicare spending: (1) unadjusted pre/post initiation test; (2) unadjusted difference-in-difference (DID) with comparison series; (3) adjusted DID; (4) propensity score (PS)-matched DID with static and dynamic baseline covariates; (5) PS-matched DID by drug adherence strata; (6) PS-matched DID for high adherers controlling for healthy adherer bias; and (7) replication for ACE-inhibitor/ARB initiators.

Data collection/extraction methods

Subjects with prevalent diabetes and no statin

SUBMITTER: Stuart B 

PROVIDER: S-EPMC4239854 | biostudies-literature | 2014 Aug

REPOSITORIES: biostudies-literature