Constitutive spectral EEG peaks in the gamma range: suppressed by sleep, reduced by mental activity and resistant to sensory stimulation.

ABSTRACT:

Objective

In a systematic study of gamma activity in neuro-psychiatric disease, we unexpectedly observed distinctive, apparently persistent, electroencephalogram (EEG) spectral peaks in the gamma range (25-100 Hz). Our objective, therefore, was to examine the incidence, distribution and some of the characteristics of these peaks.

Methods

High sample-rate, 128-channel, EEG was recorded in 603 volunteers (510 with neuropsychiatric disorders, 93 controls), whilst performing cognitive tasks, and converted to power spectra. Peaks of spectral power, including in the gamma range, were determined algorithmically for all electrodes. To determine if peaks were stable, 24-h ambulatory recordings were obtained from 16 subjects with peaks. In 10 subjects, steady-state responses to stimul

SUBMITTER: Grummett TS 

PROVIDER: S-EPMC4240063 | biostudies-literature | 2014

REPOSITORIES: biostudies-literature