Selective reporting bias of harm outcomes within studies: findings from a cohort of systematic reviews.

ABSTRACT:

Objective

To determine the extent and nature of selective non-reporting of harm outcomes in clinical studies that were eligible for inclusion in a cohort of systematic reviews.

Design

Cohort study of systematic reviews from two databases.

Setting

Outcome reporting bias in trials for harm outcomes (ORBIT II) in systematic reviews from the Cochrane Library and a separate cohort of systematic reviews of adverse events.

Participants

92 systematic reviews of randomised controlled trials and non-randomised studies published in the Cochrane Library between issue 9, 2012 and issue 2, 2013 (Cochrane cohort) and 230 systematic reviews published between 1 January 2007 and 31 December 2011 in other publications, synthesising data on harm outcomes (adverse event cohort).

SUBMITTER: Saini P 

PROVIDER: S-EPMC4240443 | biostudies-literature | 2014 Nov

REPOSITORIES: biostudies-literature