The joint in vitro action of polymyxin B and miconazole against pathogens associated with canine otitis externa from three European countries.

ABSTRACT:

Background

Canine otitis externa, an inflammation of the external ear canal, can be maintained and worsened by bacterial or fungal infections. For topical treatment, combinations of anti-inflammatory and antimicrobial ingredients are mainly used.

Hypothesis/objectives

This study was conducted to elucidate the in vitro activity of polymyxin B and miconazole against clinical bacterial isolates from three European countries, to investigate possible differences in sensitivity and to assess drug interactions.

Animals

Seventeen strains of Escherichia coli, 24 strains of Pseudomonas aeruginosa, 24 strains of Proteus mirabilis and 25 strains of Staphylococcus pseudintermedius from dogs with diagnosed otitis externa had been isolated in Germany, France and Italy.

Methods

SUBMITTER: Pietschmann S 

PROVIDER: S-EPMC4240513 | biostudies-literature | 2013 Aug

REPOSITORIES: biostudies-literature