HbA1c, fasting and 2 h plasma glucose in current, ex- and never-smokers: a meta-analysis.

ABSTRACT:

Aims/hypothesis

The relationships between smoking and glycaemic variables have not been well explored. We compared HbA1c, fasting plasma glucose (FPG) and 2 h plasma glucose (2H-PG) in current, ex- and never-smokers.

Methods

This meta-analysis used individual data from 16,886 men and 18,539 women without known diabetes in 12 DETECT-2 consortium studies and in the French Data from an Epidemiological Study on the Insulin Resistance Syndrome (DESIR) and Telecom studies. Means of three glycaemic variables in current, ex- and never-smokers were modelled by linear regression, with study as a random factor. The I (2) statistic was used to evaluate heterogeneity among studies.

Results

HbA1c was 0.10% (95% CI 0.08, 0.12) (1.1 mmol/mol [0.9, 1.3]) higher in current smokers and

SUBMITTER: Soulimane S 

PROVIDER: S-EPMC4240946 | biostudies-literature | 2014 Jan

REPOSITORIES: biostudies-literature