Association between fatty acid supplementation and prenatal stress in African Americans: a randomized controlled trial.

ABSTRACT:

Objective

To test the association between docosahexaenoic acid (DHA) supplementation and perceived stress and cortisol response to a stressor during pregnancy in a sample of African American women living in low-income environments.

Methods

Sixty-four African American women were enrolled at 16-21 weeks of gestation. Power calculations were computed using published standard deviations for the Perceived Stress Scale and the Trier Social Stress Test. Participants were randomized to either 450 mg per day of DHA (n=43) or placebo (n=21). At baseline and at 24 and 30 weeks of gestation, perceived stress was assessed by self-report. Cortisol response to a controlled stressor, the Trier Social Stress Test was measured from saliva samples collected upon arrival to the laboratory and a

SUBMITTER: Keenan K 

PROVIDER: S-EPMC4241554 | biostudies-literature | 2014 Dec

REPOSITORIES: biostudies-literature