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Bacillus anthracis pXO1 plasmid encodes a putative membrane-bound bacteriocin.


ABSTRACT: Evolutionary advantages over cousin cells in bacterial pathogens may decide about the success of a specific cell in its environment. Bacteria use a plethora of methods to defend against other cells and many devices to attack their opponents when competing for resources. Bacteriocins are antibacterial proteins that are used to eliminate competition. We report the discovery of a putative membrane-bound bacteriocin encoded by the Bacillus anthracis pathogenic pXO1 plasmid. We analyze the genomic structure of the bacteriocin operon. The proposed mechanisms of action predestine this operon as a potent competitive advantage over cohabitants of the same niche.

SUBMITTER: Perlinska A 

PROVIDER: S-EPMC4243335 | biostudies-literature | 2014

REPOSITORIES: biostudies-literature

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Bacillus anthracis pXO1 plasmid encodes a putative membrane-bound bacteriocin.

Perlińska Agata A   Grynberg Marcin M  

PeerJ 20141120


Evolutionary advantages over cousin cells in bacterial pathogens may decide about the success of a specific cell in its environment. Bacteria use a plethora of methods to defend against other cells and many devices to attack their opponents when competing for resources. Bacteriocins are antibacterial proteins that are used to eliminate competition. We report the discovery of a putative membrane-bound bacteriocin encoded by the Bacillus anthracis pathogenic pXO1 plasmid. We analyze the genomic st  ...[more]

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