Evolution of the vertebrate goose-type lysozyme gene family.

ABSTRACT:

Background

Lysozyme g is an antibacterial enzyme that was first found in the eggs of some birds, but recently has been found in additional species, including non-vertebrates. Some previously characterized lysozyme g sequences are suggested to have altered secretion potential and enzymatic activity, however the distribution of these altered sequences is unknown. Duplicated copies of the lysozyme g gene exist in some species; however, the origins of the duplicates and their roles in altered function are unclear.

Results

We identified 234 lysozyme g sequences from 118 vertebrate species, including 181 sequences that are full or near full length representing all vertebrate classes except cartilaginous fish. Phylogenetic analysis shows that most lysozyme g gene duplicates are rec

SUBMITTER: Irwin DM 

PROVIDER: S-EPMC4243810 | biostudies-literature | 2014 Aug

REPOSITORIES: biostudies-literature