Nutrigenetics and nutrigenomics insights into diabetes etiopathogenesis.

ABSTRACT: Diabetes mellitus (DM) is considered a global pandemic, and the incidence of DM continues to grow worldwide. Nutrients and dietary patterns are central issues in the prevention, development and treatment of this disease. The pathogenesis of DM is not completely understood, but nutrient-gene interactions at different levels, genetic predisposition and dietary factors appear to be involved. Nutritional genomics studies generally focus on dietary patterns according to genetic variations, the role of gene-nutrient interactions, gene-diet-phenotype interactions and epigenetic modifications caused by nutrients; these studies will facilitate an understanding of the early molecular events that occur in DM and will contribute to the identification of better biomarkers and diagnostics tools. In part

SUBMITTER: Berna G 

PROVIDER: S-EPMC4245593 | biostudies-literature | 2014 Nov

REPOSITORIES: biostudies-literature