Temporal transcriptome analysis of the chicken embryo yolk sac.

ABSTRACT:

Background

The yolk sac (YS) is an extra-embryonic tissue that surrounds the yolk and absorbs, digests and transports nutrients during incubation of the avian embryo as well as during early term mammalian embryonic development. Understanding YS functions and development may enhance the efficient transfer of nutrients and optimize embryo development. To identify temporal large-scale patterns of gene expression and gain insights into processes and mechanisms in the YS, we performed a transcriptome study of the YS of chick embryos on embryonic days (E) E13, E15, E17, E19, and E21 (hatch).

Results

3547 genes exhibited a significantly changed expression across days. Clustering and functional annotation of these genes as well as histological sectioning of the YS revealed that we m

SUBMITTER: Yadgary L 

PROVIDER: S-EPMC4246430 | biostudies-literature | 2014 Aug

REPOSITORIES: biostudies-literature