Case control study of association between the ANK3 rs10761482 polymorphism and schizophrenia in persons of Uyghur nationality living in Xinjiang China.

ABSTRACT:

Background

The rs10761482 polymorphism of the ANK3 gene has been associated with the occurrence of schizophrenia.

Aim

Assess the relationship between the ANK3 gene and schizophrenia in individuals of Uyghurian descent.

Methods

A total of 630 patients with schizophrenia and 535 healthy controls of Uyghur descent were genotyped for the ANK3 gene rs10761482 locus using Taqman probe technology. SHEsis and SPSS17.0 software were used for data analysis.

Results

There were no significant differences in the genotype or allele frequencies between the case group and control group. Within the case group there was no relationship between gender or age of onset of schizophrenia and the genotype or allele frequencies. Separate analyses among men and among women also failed t

SUBMITTER: Zhong X 

PROVIDER: S-EPMC4248261 | biostudies-literature | 2014 Oct

REPOSITORIES: biostudies-literature