Alternative treatment of serious and mild Pasteurella multocida infection in New Zealand White rabbits.

ABSTRACT:

Background

Pasteurella multocida causes numerous economically relevant diseases in livestock including rabbits. Immunisation is only variably effective. Prophylactic antibiotics are used in some species but are contra-indicated in rabbits, due to their adverse effects on the rabbit microbiota. There is therefore a substantial need for alternative forms of infection control in rabbits; we investigated the effect of oral β-glucan on P. multocida infection in this species.

Results

Thirthy-five New Zealand White rabbits were randomly divided into five groups of seven animals. Three groups were inoculated with Pasteurella multocida intranasally (in.), a physiologically appropriate challenge which reproduces naturally acquired infection, and received either (1-3), (1-6) β-glucans

SUBMITTER: Palocz O 

PROVIDER: S-EPMC4248437 | biostudies-literature | 2014 Nov

REPOSITORIES: biostudies-literature