Factors associated with in-hospital mortality in infants undergoing heart transplantation in the United States.

ABSTRACT:

Objective

Infants undergoing heart transplantation have the highest early posttransplant mortality of any age group. We sought to determine the pretransplantation factors associated with in-hospital mortality in transplanted infants in the current era.

Methods

All infants under 12 months of age who underwent primary heart transplantation during a recent 10-year period (1999-2009) in the United States were identified using the Organ Procurement and Transplant Network database. Multivariable logistic regression was used to identify independent pretransplantation factors associated with in-hospital mortality.

Results

Of 730 infants in the study (median age 3.8 months), 462 (63%) had congenital heart disease, 282 (39%) were supported by a ventilator, 94 (13%) with extraco

SUBMITTER: Gandhi R 

PROVIDER: S-EPMC4249584 | biostudies-literature | 2011 Feb

REPOSITORIES: biostudies-literature