Impact of diabetes mellitus on the prognosis of patients with hepatocellular carcinoma after curative hepatectomy.

ABSTRACT:

Background

The influence of diabetes mellitus (DM) on the prognosis of patients with hepatocellular carcinoma (HCC) remains controversial. Here we investigated the impact of DM on the prognosis of such patients after curative hepatectomy.

Methods

A consecutive cohort of 505 patients with HCC (134 with DM, 371 without) underwent curative hepatectomy were retrospectively evaluated. Postoperative morbidity and mortality, overall survival (OS) and disease-free survival (DFS) were compared between patients with or without DM. Independent prognostic predictors were identified using the Cox proportional hazards model.

Results

Patients with or without DM showed similar morbidity and 30- and 90- day mortality after curative hepatectomy (all P>0.05), as well as similar DFS at 1

SUBMITTER: Wang YY 

PROVIDER: S-EPMC4250061 | biostudies-literature | 2014

REPOSITORIES: biostudies-literature