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Limonoid and Steroidal Saponin from Azadirachta indica.

ABSTRACT: A new limonoid, 17-(5-methoxy-2-oxofuran-3-yl)-28-deoxonimbolide (1), and a new C21 steroidal saponin, 2α,4α-dihydroxy-pregn-5-en-16-one-3α-O-D-glucopyranoside (2), together with 11 known compounds were isolated from the methanol extract of the leaves of Azadirachta indica. The structures were elucidated by means of spectroscopic analysis and putative biosynthetic origins. All the compounds were evaluated for their antibacterial activities against six bacterial strains.

SUBMITTER: Liu L

PROVIDER: S-EPMC4250567 | biostudies-literature | 2014 Dec

REPOSITORIES: biostudies-literature

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Limonoid and Steroidal Saponin from Azadirachta indica.

Liu Lu L Zhao Yun-Li YL Cheng Gui-Guang GG Chen Ying-Ying YY Qin Xu-Jie XJ Song Chang-Wei CW Yang Xing-Wei XW Liu Ya-Ping YP Luo Xiao-Dong XD

Natural products and bioprospecting 20141108 6

A new limonoid, 17-(5-methoxy-2-oxofuran-3-yl)-28-deoxonimbolide (1), and a new C21 steroidal saponin, 2α,4α-dihydroxy-pregn-5-en-16-one-3α-O-D-glucopyranoside (2), together with 11 known compounds were isolated from the methanol extract of the leaves of Azadirachta indica. The structures were elucidated by means of spectroscopic analysis and putative biosynthetic origins. All the compounds were evaluated for their antibacterial activities against six bacterial strains. ...[more]

PMID: 25381190

Dataset Information

Limonoid and Steroidal Saponin from Azadirachta indica.

Publications

Limonoid and Steroidal Saponin from Azadirachta indica.

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