AromaDeg, a novel database for phylogenomics of aerobic bacterial degradation of aromatics.

ABSTRACT: Understanding prokaryotic transformation of recalcitrant pollutants and the in-situ metabolic nets require the integration of massive amounts of biological data. Decades of biochemical studies together with novel next-generation sequencing data have exponentially increased information on aerobic aromatic degradation pathways. However, the majority of protein sequences in public databases have not been experimentally characterized and homology-based methods are still the most routinely used approach to assign protein function, allowing the propagation of misannotations. AromaDeg is a web-based resource targeting aerobic degradation of aromatics that comprises recently updated (September 2013) and manually curated databases constructed based on a phylogenomic approach. Grounded in phylogenet

SUBMITTER: Duarte M 

PROVIDER: S-EPMC4250580 | biostudies-literature | 2014

REPOSITORIES: biostudies-literature