Divergence of protein-coding capacity and regulation in the Bacillus cereus sensu lato group.

ABSTRACT:

Background

The Bacillus cereus sensu lato group contains ubiquitous facultative anaerobic soil-borne Gram-positive spore-forming bacilli. Molecular phylogeny and comparative genome sequencing have suggested that these organisms should be classified as a single species. While clonal in nature, there do not appear to be species-specific clonal lineages, excepting B. anthracis, in spite of the wide array of phenotypes displayed by these organisms.

Results

We compared the protein-coding content of 201 B. cereus sensu lato genomes to characterize differences and understand the consequences of these differences on biological function. From this larger group we selected a subset consisting of 25 whole genomes for deeper analysis. Cluster analysis of orthologous proteins grouped the

SUBMITTER: Toby IT 

PROVIDER: S-EPMC4251056 | biostudies-literature | 2014

REPOSITORIES: biostudies-literature