Treatment for overweight and obesity in adult populations: a systematic review and meta-analysis.

ABSTRACT:

Background

Obesity is a major public health issue. This review updates the evidence on the effectiveness of behavioural and pharmacologic treatments for overweight and obesity in adults.

Methods

We updated the search conducted in a previous review. Randomized trials of primary-care-relevant behavioural (diet, exercise and lifestyle) and pharmacologic (orlistat and metformin) with or without behavioural treatments in overweight and obese adults were included if 12-month, postbaseline data were provided for weight outcomes. Studies reporting harms were included regardless of design. Data were extracted and pooled wherever possible for 5 weight outcomes, 6 secondary health outcomes and 4 adverse events categories.

Results

We identified 68 studies, most consisted of short

SUBMITTER: Peirson L 

PROVIDER: S-EPMC4251513 | biostudies-literature | 2014 Oct

REPOSITORIES: biostudies-literature