Use of benzodiazepines and related drugs in Manitoba: a population-based study.

ABSTRACT:

Background

Despite their favourable toxicology profile, benzodiazepines and the related Z-drugs (zopiclone, zolpidem and zaleplon) have been associated with physiological tolerance, dependence and addiction. Evidence of harm (e.g., falls, motor vehicle collisions and cognitive disturbances) has been reported in older populations. The aim of this study was to determine the relation between users' characteristics and the use of benzodiazepines and Z-drugs in Manitoba over a 16-year period.

Methods

This time-series analysis was based on prescription data from Apr. 1, 1996, to Mar. 31, 2012, obtained from the Drug Product Information Network database of Manitoba. We obtained sociodemographic information on benzodiazepine and Z-drug users from the Population Registry and determin

SUBMITTER: Alessi-Severini S 

PROVIDER: S-EPMC4251517 | biostudies-literature | 2014 Oct

REPOSITORIES: biostudies-literature