Template based rotation: a method for functional connectivity analysis with a priori templates.

ABSTRACT: Functional connectivity magnetic resonance imaging (fcMRI) is a powerful tool for understanding the network level organization of the brain in research settings and is increasingly being used to study large-scale neuronal network degeneration in clinical trial settings. Presently, a variety of techniques, including seed-based correlation analysis and group independent components analysis (with either dual regression or back projection) are commonly employed to compute functional connectivity metrics. In the present report, we introduce template based rotation,(1) a novel analytic approach optimized for use with a priori network parcellations, which may be particularly useful in clinical trial settings. Template based rotation was designed to leverage the stable spatial patterns of intrinsi

SUBMITTER: Schultz AP 

PROVIDER: S-EPMC4252576 | biostudies-literature | 2014 Nov

REPOSITORIES: biostudies-literature