Early attained weight and length predict growth faltering better than velocity measures in infants with CF.

ABSTRACT:

Background

CF infants often do not grow as expected which adversely affects later clinical outcomes, thus sensitive early measures of growth deficiency are important. This study compared attained growth for age with velocity standards to determine which better predicts growth deficits at 24 months of age.

Methods

Growth deficiency in infancy based on weight and length velocity, and attained growth was calculated for 1992 infants in the US CF Foundation National Registry using the World Health Organization (WHO) and US growth standards. One, two and three month increments were used for calculating velocity and pooled for each age interval. Sensitivity and specificity of early indicators to predict growth deficiency at 24 months were calculated.

Results

Observed prevale

SUBMITTER: Heltshe SL 

PROVIDER: S-EPMC4252713 | biostudies-literature | 2014 Dec

REPOSITORIES: biostudies-literature