Dynamics of midgut microflora and dengue virus impact on life history traits in Aedes aegypti.

ABSTRACT: Significant morbidity and potential mortality following dengue virus infection is a re-emerging global health problem. Due to the limited effectiveness of current disease control methods, mosquito biologists have been searching for new methods of controlling dengue transmission. While much effort has concentrated on determining genetic aspects to vector competence, paratransgenetic approaches could also uncover novel vector control strategies. The interactions of mosquito midgut microflora and pathogens may play significant roles in vector biology. However, little work has been done to see how the microbiome influences the host's fitness and ultimately vector competence. Here we investigated the effects of the midgut microbial environment and dengue infection on several fitness characteris

SUBMITTER: Hill CL 

PROVIDER: S-EPMC4253069 | biostudies-literature | 2014 Dec

REPOSITORIES: biostudies-literature