Chimera: a Bioconductor package for secondary analysis of fusion products.

ABSTRACT:

Summary

Chimera is a Bioconductor package that organizes, annotates, analyses and validates fusions reported by different fusion detection tools; current implementation can deal with output from bellerophontes, chimeraScan, deFuse, fusionCatcher, FusionFinder, FusionHunter, FusionMap, mapSplice, Rsubread, tophat-fusion and STAR. The core of Chimera is a fusion data structure that can store fusion events detected with any of the aforementioned tools. Fusions are then easily manipulated with standard R functions or through the set of functionalities specifically developed in Chimera with the aim of supporting the user in managing fusions and discriminating false-positive results.

SUBMITTER: Beccuti M 

PROVIDER: S-EPMC4253834 | biostudies-literature | 2014 Dec

REPOSITORIES: biostudies-literature