Effects of vitamin C and E supplementation on endogenous antioxidant systems and heat shock proteins in response to endurance training.

ABSTRACT: Reactive oxygen and nitrogen species are important signal molecules for adaptations to training. Due to the antioxidant properties of vitamin C and E, supplementation has been shown to blunt adaptations to endurance training. In this study, we investigated the effects of vitamin C and E supplementation and endurance training on adaptations in endogenous antioxidants and heat shock proteins (HSP). Thirty seven males and females were randomly assigned to receive Vitamin C and E (C + E; C: 1000 mg, E: 235 mg daily) or placebo (PLA), and underwent endurance training for 11 weeks. After 5 weeks, a subgroup conducted a high intensity interval session to investigate acute stress responses. Muscle and blood samples were obtained to investigate changes in proteins and mRNA related to the antioxidan

SUBMITTER: Cumming KT 

PROVIDER: S-EPMC4254089 | biostudies-literature | 2014 Oct

REPOSITORIES: biostudies-literature