Efficacy of mycophenolate mofetil in sarcoidosis.

ABSTRACT:

Background

Immunosuppressive (IS) therapy is indicated to treat progressive sarcoidosis, but randomized controlled trials to guide physicians in the use of steroid sparing agents are lacking. The aim of this retrospective study was to examine the role of mycophenolate mofetil (MMF) as an alternative therapy in the treatment of sarcoidosis.

Methods

A retrospective chart review of all patients who had been prescribed MMF between January 2008 and October 2011 was conducted. Patients with insufficient data or who had another IS therapy initiated concomitantly with MMF, including prednisone, were excluded. Physiological data obtained at the time MMF therapy was initiated as well as six and twelve months before and after therapy was extracted. Longitudinal analyses of the effect o

SUBMITTER: Hamzeh N 

PROVIDER: S-EPMC4254196 | biostudies-literature | 2014 Nov

REPOSITORIES: biostudies-literature