Ovarian cancer-related hypophosphatemic osteomalacia--a case report.

ABSTRACT:

Context

Tumor-induced osteomalacia (TIO) is a rare paraneoplastic syndrome caused primarily by benign mesenchymal tumors. It has been associated with malignancies in rare cases. High serum levels of fibroblast growth factor (FGF) 23 reported in a group of patients with ovarian cancer had normal serum phosphate levels. There had been no ovarian cancer-related hypophosphatemic osteomalacia in a search of the literature.

Objective

We investigated a 57-year-old woman with progressive low back pain.

Design and intervention

Clinical, biochemical, and radiological assessments were performed. The patient's serum phosphate and FGF23 levels were evaluated at baseline and after treatment for ovarian cancer.

Results

The patient presented with progressive low back pain and

SUBMITTER: Lin HA 

PROVIDER: S-EPMC4255128 | biostudies-literature | 2014 Dec

REPOSITORIES: biostudies-literature