Urinary biomonitoring of phosphate flame retardants: levels in California adults and recommendations for future studies.

ABSTRACT: Phosphate flame retardants (PFRs) are abundant and found at the highest concentrations relative to other flame retardant chemicals in house dust; however, little is known about the biological levels of PFRs and their relationship with house dust concentrations. These relationships provide insight into major exposure pathways and potential health risks. We analyzed urine samples from 16 California residents in 2011 for 6 chlorinated and nonchlorinated dialkyl or diaryl phosphates (DAPs), the expected major metabolites of the most prominent PFRs, and qualitatively screened for 18 other metabolites predicted from in vitro studies. We detected all 6 DAPs within the range of previously reported levels, although very few comparisons are available. We found weakly positive nonsignificant correlat

SUBMITTER: Dodson RE 

PROVIDER: S-EPMC4255275 | biostudies-literature | 2014 Dec

REPOSITORIES: biostudies-literature