The effectiveness of flow cytometric sorting of human sperm (MicroSort®) for influencing a child's sex.

ABSTRACT:

Background

Flow cytometric sorting can be used to separate sperm based on sex chromosome content. Differential fluorescence emitted by stained X- vs. Y-chromosome-bearing sperm enables sorting and collection of samples enriched in either X- or Y-bearing sperm for use to influence the likelihood that the offspring will be a particular sex. Herein we report the effectiveness of flow cytometric sorting of human sperm and its use in human ART procedures.

Methods

This prospective, observational cohort study of the series of subjects treated with flow cytometrically sorted human sperm was conducted at investigational sites at two private reproductive centers. After meeting inclusion criteria, married couples (n = 4993) enrolled to reduce the likelihood of sex-linked or sex-limited

SUBMITTER: Karabinus DS 

PROVIDER: S-EPMC4256056 | biostudies-literature | 2014 Nov

REPOSITORIES: biostudies-literature