Comparative analysis of surface-exposed virulence factors of Acinetobacter baumannii.

ABSTRACT:

Background

Acinetobacter baumannii is a significant hospital pathogen, particularly due to the dissemination of highly multidrug resistant isolates. Genome data have revealed that A. baumannii is highly genetically diverse, which correlates with major variations seen at the phenotypic level. Thus far, comparative genomic studies have been aimed at identifying resistance determinants in A. baumannii. In this study, we extend and expand on these analyses to gain greater insight into the virulence factors across eight A. baumannii strains which are clonally, temporally and geographically distinct, and includes an isolate considered non-pathogenic and a community-acquired A. baumannii.

Results

We have identified a large number of genes in the A. baumannii genomes that are known

SUBMITTER: Eijkelkamp BA 

PROVIDER: S-EPMC4256060 | biostudies-literature | 2014 Nov

REPOSITORIES: biostudies-literature