An updated insight into the Sialotranscriptome of Triatoma infestans: developmental stage and geographic variations.

ABSTRACT:

Background

Triatoma infestans is the main vector of Chagas disease in South America. As in all hematophagous arthropods, its saliva contains a complex cocktail that assists blood feeding by preventing platelet aggregation and blood clotting and promoting vasodilation. These salivary components can be immunologically recognized by their vector's hosts and targeted with antibodies that might disrupt blood feeding. These antibodies can be used to detect vector exposure using immunoassays. Antibodies may also contribute to the fast evolution of the salivary cocktail.

Methodology

Salivary gland cDNA libraries from nymphal and adult T. infestans of breeding colonies originating from different locations (Argentina, Chile, Peru and Bolivia), and cDNA libraries originating from F1 po

SUBMITTER: Schwarz A 

PROVIDER: S-EPMC4256203 | biostudies-literature | 2014 Dec

REPOSITORIES: biostudies-literature