Albumin versus other fluids for fluid resuscitation in patients with sepsis: a meta-analysis.

ABSTRACT:

Background

Early fluid resuscitation is vital to patients with sepsis. However, the choice of fluid has been a hot topic of discussion. The objective of this study was to evaluate whether the use of albumin-containing fluids for resuscitation in patients with sepsis was associated with a decreased mortality rate.

Methods

We systematically searched PubMed, EMBASE and Cochrane library for eligible randomized controlled trials (RCTs) up to March 2014. The selection of eligible studies, assessment of methodological quality, and extraction of all relevant data were conducted by two authors independently.

Results

In total, 15 RCTs were eligible for analysis. After pooling the data, we found there was no significant effect of albumin-containing fluids on mortality in patient

SUBMITTER: Jiang L 

PROVIDER: S-EPMC4256427 | biostudies-literature | 2014

REPOSITORIES: biostudies-literature