MicroRNAs influence reproductive responses by females to male sex peptide in Drosophila melanogaster.

ABSTRACT: Across taxa, female behavior and physiology change significantly following the receipt of ejaculate molecules during mating. For example, receipt of sex peptide (SP) in female Drosophila melanogaster significantly alters female receptivity, egg production, lifespan, hormone levels, immunity, sleep, and feeding patterns. These changes are underpinned by distinct tissue- and time-specific changes in diverse sets of mRNAs. However, little is yet known about the regulation of these gene expression changes, and hence the potential role of microRNAs (miRNAs), in female postmating responses. A preliminary screen of genomic responses in females to receipt of SP suggested that there were changes in the expression of several miRNAs. Here we tested directly whether females lacking four of the candida

SUBMITTER: Fricke C 

PROVIDER: S-EPMC4256774 | biostudies-literature | 2014 Dec

REPOSITORIES: biostudies-literature