Validation of disability status, a claims-based measure of functional status for cancer treatment and outcomes studies.

ABSTRACT:

Background

In prior research, we developed a claims-based prediction model for poor patient disability status (DS), a proxy measure for performance status, commonly used by oncologists to summarize patient functional status and assess ability of a patient to tolerate aggressive treatment. In this study, we implemented and validated the DS measure in 4 cohorts of cancer patients: early and advanced non-small cell lung cancers (NSCLC), stage IV estrogen receptor-negative (ER-) breast cancer, and myelodysplastic syndromes (MDS).

Data and methods

SEER-Medicare data (1999-2007) for the 4 cohorts of cancer patients. Bivariate and multivariate logistic regression tested the association of the DS measure with designated cancer-directed treatments: early NSCLC (surgery), advanced NSC

SUBMITTER: Davidoff AJ 

PROVIDER: S-EPMC4256940 | biostudies-literature | 2014 Jun

REPOSITORIES: biostudies-literature