Comparative transcriptome analysis reveals early pregnancy-specific genes expressed in peripheral blood of pregnant sows.

ABSTRACT: Early and accurate diagnosis of pregnancy is important for effective management of an economical pig farm. Besides the currently available methods used in early diagnosis of sows, circulating nucleic acids in peripheral blood may contain some early pregnancy-specific molecular markers. For the first time, microarray analysis of peripheral blood from pregnant sows versus non-pregnant sows identified 127 up-regulated and 56 down-regulated genes at day 14 post-insemination. Gene Ontology annotation grouped the total differently expressed genes into 3 significantly enriched terms, cell surface receptor linked signal transduction, G-protein coupled receptor protein signaling pathway and regulation of vesicle-mediated transport. Signaling pathway analysis revealed the only one significantly chan

SUBMITTER: Shen J 

PROVIDER: S-EPMC4257664 | biostudies-literature | 2014

REPOSITORIES: biostudies-literature