Oral administration of morphine versus ibuprofen to manage postfracture pain in children: a randomized trial.

ABSTRACT:

Background

Recent warnings from Health Canada regarding codeine for children have led to increased use of nonsteroidal anti-inflammatory drugs and morphine for common injuries such as fractures. Our objective was to determine whether morphine administered orally has superior efficacy to ibuprofen in fracture-related pain.

Methods

We used a parallel group, randomized, blinded superiority design. Children who presented to the emergency department with an uncomplicated extremity fracture were randomly assigned to receive either morphine (0.5 mg/kg orally) or ibuprofen (10 mg/kg) for 24 hours after discharge. Our primary outcome was the change in pain score using the Faces Pain Scale - Revised (FPS-R). Participants were asked to record pain scores immediately before and 30 minut

SUBMITTER: Poonai N 

PROVIDER: S-EPMC4259768 | biostudies-literature | 2014 Dec

REPOSITORIES: biostudies-literature