Synthesis of (±)-tetrapetalone A-Me aglycon.

ABSTRACT: The first synthesis of (±)-tetrapetalone A-Me aglycon is described. Key bond-forming reactions include Nazarov cyclization, a ring-closing metathesis promoted with complete diastereoselectivity by a chiral molybdenum-based complex, tandem conjugate reduction/intramolecular aldol cyclization, and oxidative dearomatization.

SUBMITTER: Carlsen PN 

PROVIDER: S-EPMC4260470 | biostudies-literature | 2014 Aug

REPOSITORIES: biostudies-literature