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Coronary artery disease and outcomes of aortic valve replacement for severe aortic stenosis.


ABSTRACT:

Objectives

The study sought to contrast risk profiles and compare outcomes of patients with severe aortic stenosis (AS) and coronary artery disease (CAD) who underwent aortic valve replacement (AVR) and coronary artery bypass grafting (AS+CABG) with those of patients with isolated AS who underwent AVR alone.

Background

In patients with severe AS, CAD is often an incidental finding with underappreciated survival implications.

Methods

From October 1991 to July 2010, 2,286 patients underwent AVR+CABG and 1,637 AVR alone. A propensity score was developed and used for matched comparisons of outcomes (1,082 patient pairs). Analyses of long-term mortality were performed for each group, then combined to identify common and unique risk factors.

Results

Patients with AS+

SUBMITTER: Beach JM 

PROVIDER: S-EPMC4262244 | biostudies-literature | 2013 Feb

REPOSITORIES: biostudies-literature